J Soc Obstet Gynaecol Can 1997 Publication number 61 June 1997
National Consensus Statement on the Prevention of
Early-Onset Group B Streptococcal Infections in the Newborn
Society of Obstetricians and Gynaecologists of Canada
Canadian Paediatric Society
Identification and management of women whose newborns
might be at increased risk of GBS disease are acceptable by either of two methods:
a. Universal screening of all pregnant women at 35 to 37 weeks gestation with a single combined
vaginal-anorectal swab and the offer of intrapartum chemoprophylaxis to all GBS-colonized
b. No universal screening but intrapartum chemoprophylaxis for all women with identified risk
factors (Table 2). This strategy should also be used in cases where universal screening is the
policy but either was not done or the test results are not available.
Risk Factors For Which Intrapartum
Chemoprophylaxis is Recommended
- Pre-term labour (< 37 weeks gestation)
- Term labour (>= 37 weeks gestation)
- Prolonged rupture of membranes. Chemoprophylaxis should be given if labour and/or
ruptured membranes is likely to continue beyond 18 hours (neonatal benefits are
optimally achieved if antibiotics are given at least 4 hours prior to delivery).
- Maternal fever during labour (>38 deg C orally).
- Previous delivery of a newborn with GBS disease regardless of current GBS colonization status
- Previously documented GBS bacteriuria